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C. L. Wong, Dave

DAVE
黃至樂/C. L. Wong, Dave

副教授/Associate Professor 

Department of Electrical Engineering 

Chang Gung University, Taiwan 

電話/TEL:886-3-2118800-5677

信箱/Email:clwong@mail.cgu.edu.tw

Research areas:

Biomedical Optics, Surface Plasmon Resonance Imaging Biosensors,

Plasmonic and Metamaterial Biosensors for Infectious Diseases and Cancer Diagnosis.

Lab: Eng. Building, 7F, Biomedical Sensors Laboratory (生醫光學傳感器實驗室)

Biography

Chi Lok Wong is an Associate Professor at the Department of Electrical Engineering, Chang Gung University. He received his Ph.D. degree in Applied Physics (Photonics) from the City University of Hong Kong in 2007. After that, he took a research position at Chinese University of Hong Kong. In 2008, he joined the School of Electrical and Electronic Engineering, Nanyang Technological University Singapore as a Research Fellow working in the area of Biophotonics. Between 2012-2021, he was a Research Fellow/ Senior Research Fellow at the Institute of Bioengineering and Bioimaging, Agency of Science, Technology and Research (A*STAR Singapore) before joining Chang Gung University as Associate Professor in 2021. His research interest is on Biomedical Optics, Surface Plasmon Resonance Imaging Biosensors, Plasmonic and Metamaterial Biosensors for rapid infectious diseases and cancer diagnosis.

Publication list

  1. Journal papers

    24.  Chi Lok Wong, Sau Yeen Loke, Hann Qian Lim, Ghayathri Balasundaram,

    Patrick Chan, Bee Kiang Chong, Ern Yu Tan, Ann Siew Gek Lee, Malini Olivo,

    Circulating microRNA breast cancer biomarker detection in patient sera with

    surface plasmon resonance imaging biosensor,

    Journal of Biophotonics (impact factor 3.2), e202100153, (2021)

    23.  Shuyan Zhang, Chi Lok Wong, Shuwen Zeng, Renzhe Bi, Kolvyn Tai, Kishan

    Dholakia, Malini Olivo, Metasurfaces for biomedical applications: imaging and

    sensing from a nanophotonics perspective,

    Nanophotonics (impact factor 7.4) v10 (1), pp. 259-293, (2021)

    22.  Chi Lok Wong, Jia Yee Chan, LX Choo, HQ Lim, H Mittman, M Olivo

    Plasmonic Contrast Imaging Biosensor for the Detection of H3N2 Influenza Protein-Antibody and DNA-DNA Molecular Binding,

    IEEE Sensors Journal (impact factor 3.0) v19 (24), pp. 11828-11833, (2019)

    21.  CL Wong, M Chua, H Mittman, LX Choo, HQ Lim, M Olivo

    A Phase-Intensity Surface Plasmon Resonance Biosensor for Avian Influenza A (H5N1) Detection, Sensors (impact factor 3.2) 17:10, 2363, (2017)

    20.  U. S. Dinish*, Chi Lok Wong*, Sandhya Sriram*, Ong Wee Kiat, Ghayathri

    Balasundaram, Shigeki Sugii, Malini Olivo, (* Joint first authors)

    Diffuse Optical Spectroscopy and Imaging to Detect and Quantify Adipose Tissue Browning, Scientific Report (impact factor – 3.9) 7:41357 (2017)

    19.  Chi Lok Wong, U.S. Dinish, Malini Olivo

    Recent advances in SPR and SERS for sensitive translational medical diagnostics

    Photonics & Lasers in Medicine, v4(2), pp. 119–149 (2015)

    18.  Chi Lok Wong and Malini Olivo (Invited)

    Surface Plasmon Resonance Imaging Sensors: A Review

    Plasmonics (impact factor 2.9) v9(4), pp 809-824 (2014) Citation 212

    17.  Chi Lok Wong, U.S. Dinish, Michael S Schmidt, Malini Olivo,

    Non-labeling Multiplex Surface Enhanced Raman Scattering (SERS) Detection of Volatile Organic Compounds (VOCs),

    Analytica Chimica Acta (impact factor – 5.9) v844, pp. 54–60, (2014) Citation 48

    16.  Chi Lok Wong, U.S. Dinish, K.D. Buddharaju, Michael Stenbæk Schmidt and Malini Olivo, Surface Enhanced Raman Scattering (SERS) based Volatile Organic Compounds (VOCs) Detection   using Plasmonic Bimetallic Nanogap Substrate,

    Applied Physics A, v117(2), pp 687-692 (2014)

    15.  Chris Jun Hui Ho, Ghayathri Balasundaram, Wouter Driessen, Ross McLaren,

    Chi Lok Wong, US Dinish, Amalina Binte Ebrahim Attia, Vasilis Ntziachristos, Malini Olivo, Multifunctional photosensitizer-based contrast agents for photoacoustic imaging,

    Scientific Reports (impact factor – 3.9) v4:5342, (2014) Citation 116

    14.  Chris Jun Hui Ho, Kai Li, Ghayathri Balasundaram, Wouter Driessen,

    Dinish U. S., Chi Lok Wong, Jie Liu, Vasilis Ntziachristos, Bin Liu, Malini Olivo,

    Molecular photoacoustic imaging of breast cancer using an actively targeted conjugated polymer,

    International Journal of Nanomedicine (impact factor – 4.4)

    2015:10 387–397 (2015) Citation 42

    13.  Chi Lok Wong, George Chung Kit Chen, Xiaochao Li, Beng Koon Ng, Ping Shum, Peng Chen, Zhiping Lin, Chinlon Lin, Malini Olivo, Colorimetric surface plasmon resonance imaging (SPRI) biosensor array based on polarization orientation,                                          Biosensors and Bioelectronics 47 (impact factor – 10.2), pp. 545–552, (2013)

     

    12.  Chi Lok Wong, George Chung Kit Chen, Beng Koon Ng, Shuchi Agarwal,  Zhiping Lin, Peng Chen, and Ho Pui Ho, Multiplex spectral surface plasmon resonance imaging (SPRI) sensor based on the polarization control scheme, Optics Express (impact factor – 3.6) 19, 18965-18978, (2011)

    11.  Chi Lok Wong, George C. K. Chen, Beng Koon Ng, Shuchi Agarwal, Nolang Fanani, Zhiping Lin, Srivathsan Vasudevan and Peng Chen, Photothermal imaging of nanoparticles beyond the diffraction limit, Optical Engineering 50, pp. 073201, (2011)

    10.  Chi Lok Wong, George C.K. Chen, Teu Choon Kiat, Srivathsan Vasudevan, Pham Thuy Anh, Niladri Bihari Puhan, Marta Andika, Shuchi Agarwal, Zhi Ping Lin, Peng Chen, Photothermal imaging (PTI) system for the imaging of gold nano-particles and cellular organelles, Advanced Materials Research v74, pp. 45-48, (2009).

    9.   C. L. Wong, H.P. Ho, Y.K. Suen, S.K. Kong, Q.L. Chen, W. Yuan, S.Y. Wu,

    Real-time protein biosensor arrays based on surface plasmon resonance differential phase imaging, Biosensors and Bioelectronics 24(4) (impact factor – 10.2), pp. 606-612, (2008) Citation 81

    8.   C.L. Wong, H.P. Ho, K.S. Chan, P.L. Wong, S.Y. Wu, Chinlon Lin,

    Optical characterization of elastohydrodynamic lubricated (EHL) contacts using surface plasmon resonance (SPR) effect,

    Tribology International (impact factor 4.2) 41(5), pp. 356-366, (2008)

    7.   C.L. Wong, H.P. Ho, T. T. Yu, Y.K. Suen, W. Y. Chow, S.Y. Wu, W.C. Law, W Yuan, W.J. Li, S.K. Kong and Chinlon Lin, Two-dimensional biosensor arrays based on surface plasmon resonance phase imaging, Applied Optics 46, pp. 2325-2332, (2007) Citation 48

    6.   W. Yuan, H. P. Ho, C. L. Wong, S.Y. Wu, Y. K. Suen, S. K. Kong and

    Chinlon Lin, Surface Plasmon Resonance Biosensor Incorporated in a Michelson Interferometer With Enhanced Sensitivity,

    IEEE Sensors Journal (impact factor 3.0) 7(1), pp. 70-73, (2007) Citation 66

    5.   W. Yuan, H. P. Ho, C. L. Wong, S.Y. Wu, Y. K. Suen, S. K. Kong and

    Chinlon Lin, Sensitivity enhancement based on application of multi-pass interferometry in phase-sensitive surface plasmon resonance biosensor, 

    Optics Communications 275 (2), pp. 491-496, (2007) Citation 75

    4.   H. P. Ho, C.L. Wong, K.S. Chan, S.Y. Wu and Chinlon Lin,

    Application of 2-D spectral surface plasmon resonance to the imaging of pressure distribution in elastohydrodynamic (EHD) lubricant films,

    Applied Optics 45, pp. 5819-5826, (2006) Cover page of that issue

    3.   C.L. Wong, H.P. Ho, K.S. Chan, and S.Y. Wu and Chinlon Lin,

    Application of surface plasmon resonance sensing to studying elastohydrodynamic lubricant films, Applied Optics 44, pp. 4830-4837, (2005)

    2.   Chi Lok Wong, Ho-Pui Ho, Kwok-Sum Chan, Shu-Yuen Wu and Chinlon Lin,

    Application of spectral surface plasmon resonance to gas pressure sensing,

    Optical Engineering 44, pp. 124403, (2005) Citation 35

    1.   W. W. Lam, L. H. Chu, C. L. Wong and Y. T. Zhang,

    A surface plasmon resonance system for the measurement of glucose in aqueous

    solution, Sensors and Actuators B: Chemical (impact factor – 7.1) 105(2),

    pp. 138-143, (2005) Citation 93

    Patent

    Patent Licensing NT$ 1 Million - Licensed by Intellextual Ventures Holding 29 LLC

    U.S. Patent (2009) Patent no – US 7623246 B2

    H.P. Ho, C. L. Wong, S.Y. Wu, W.C. Law, Chinlon Lin and S.K. Kong,

    Optical sensing devices with SPR sensors based on differential phase interrogation and measuring method using the same.

    9.  PCT Patent Pending (10/1/2019) Application no. WO2019009806A1

    Jun Hui Ho Chris, Renzhe Bi, Chi Lok Wong, Malini Olivo, Tao Yang,

    Zhongkang Lu, Weimin Huang, Kapil Dev,

    8.  PCT Patent Pending (25/1/2018) Application no: WO2018017017A1

    Chi Lok Wong and Malini Olivo,

    7.  U.S. Patent (pending) (23/10/2018) Application no: US10107748B2

    Chi Lok Wong and Malini Olivo,

    6.  E.U. Patent (pending) (5/7/2017) Application no.: EP3066455A4

    Chi Lok Wong and Malini Olivo,

    5.  PCT Patent (26/2/2015) Application no: WO2015026297A1

    Malini Olivo, Chi Lok Wong and U.S. Dinish

    4.  U.S. Patent (pending) (27/10/2016) Application no: US20160310010A1

    Malini Olivo, Jun Hui Ho, US Dinish, Chi Lok Wong, B. Ghayathri,

    3.  E.U. Patent (pending) (31/5/2017) Application no: EP3076860A4

    Malini Olivo, Jun Hui Ho, US Dinish, Chi Lok Wong, B. Ghayathri,

    2.  Singapore Provisional Patent (Filed at 2011) Application no: 201100967-7,

    Chi Lok Wong, Beng Koon Ng, George C. K. Chen, Shuchi Agarwal,

    Zhiping Lin and Peng Chen, Multiplex spectral surface resonance imaging (SPRI) sensor based on polarization control scheme.

    1.  U.S. Patent (2009) Patent no – US 7623246 B2

    H.P. Ho, C. L. Wong, S.Y. Wu, W.C. Law, Chinlon Lin and S.K. Kong,

    Optical sensing devices with SPR sensors based on differential phase interrogation and measuring method using the same.

    Book Chapter

    Chi Lok Wong, X. Yu, P. Shum and H.P. Ho,

    Optical Characterization of Elastohydrodynamic Lubrication Pressure with

    Surface Plasmon Resonance,

    New Tribological Ways, ISBN 978-953-307-206-7, (2011).

    Conference paper

    Award

    Best Student Paper

    C.L. Wong, H.P. Ho, Y.K. Suen, C. W. Yin, W.J. Li, S.K. Kong and Chinlon Lin,

    Biosensor arrays based on surface plasmon resonance phase imaging, International

    Symposium on Biophotonics, Nanophotonics and Metamaterials, Hangzhou, China,

    pp. 102-105, Oct 16-18th (2006).

    13.  Chi Lok Wong, U.S. Dinish, Kavitha Devi Buddharaju and Malini Olivo, Volatile Organic Compounds (VOCs) Detection with Surface Enhanced Raman Scattering (SERS) based on Plasmonic Bimetallic Nanogap Substrate, META 2014 Conference 20-23th May 2014, Singapore.

    12.  C. L. Wong, G. Chen, and B. K. Ng, Two-dimensional Surface Plasmon Resonance (SPR) Biosensor based on Infrared Imaging, Optical Molecular Probes, Imaging and Drug Delivery, Optical Society of America, (2011).

    11.  C.L. Wong, H.P. Ho, Y.K. Suen, C. W. Yin, W.J. Li, S.K. Kong and Chinlon Lin, Biosensor arrays based on surface plasmon resonance phase imaging, International Symposium on Biophotonics, Nanophotonics and Metamaterials, Hangzhou, China, pp. 102-105, Oct 16-18th (2006).

    10.  Wu Yuen, C.L. Wong, S.Y. Wu, H.P. Ho, S.K. Kong and Chinlon Lin, Application of Fabry-Perot interferometer for signal amplification in phase-sensitive surface plasmon resonance biosensors, Biosensors 2006, The 9th World Congress on Biosensors, Toronto, Canada, 10 -12 May (2006).

    9.  H. P. Ho and C. L. Wong, Imaging Differential Phase Surface Plasmon Resonance Biosensors, Lasers and Electro-Optics Society, 2006. LEOS 2006. 19th Annual Meeting of the IEEE, pp. 675 - 676, Oct. (2006).

    8.  Ho, H.P., Wong, C.L., Wu, S.Y. Yuan, W. Lin, C. Kong, S.K., Highly Sensitive Photonic Biosensors Based on Interferometric Detection of Surface Plasmon Waves, Biophotonics, Nanophotonics and Metamaterials, 2006, P.2, 16-18 Oct. (2006).

    7.  W. Yuan, H. P. Ho, C. L. Wong, S.Y. Wu, Y. K. Suen, S. K. Kong, Chinlon Lin, Sensitivity enhancement of phase-sensitive surface plasmon resonance biosensor using multi-pass interferometry, International Symposium on Biophotonics, Nanophotonics and Metamaterials, Hangzhou, China, pp. 209-212, Oct 16-18th (2006).

    6.  Kin Fong Lei, Wing Cheung Law, Chi Lok Wong, Li, W.J. Ho Pui Ho, Siu-Kai Kong and Chinlon Lin, Robotics and Biomimetics (ROBIO), pp. 309 - 313, 16 October (2006).

    5.  Chi Lok Wong, Kin Fong Lei, Winnie W. Y. Chow, Ho Pui Ho, Wen J. Li, Siu-Kai Kong and Kwok Sum Chan, Chemical and Biological Detection using Microfluidic Platform and Surface Plasmon Resonance Imaging Sensor, The 4th IEEE Conference on Sensor, Irvine, CA, USA, Oct 31 - Nov 3, (2005).

    4.  H. P. Ho, K. S. Chan, C. L. Wong, K. F. Lei, W. J. Li, W. C. Law, S. Y. Wu, S. K. Kong, Chinlon Lin, Proc. SPIE Vol. 5927, pp. 84-93, Aug (2005).

    3.  H.P. Ho, C.L. Wong, K.F. Lei, W.J. Li, K.S. Chan, W.C. Law, S.Y. Wu, S.K. Kong and Chinlon Lin, Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform, IEEE Conference on Electron Devices and Solid-State Circuits, Hong Kong, 19-21 December (2005).

    2.  Wong, C.L., Ho, H.P., Wong, P.L., Wu, S.Y. and Guo, F., Application of surface plasmon resonance to measurement of hydrostatic pressure in Tribological lubricant layers. Electron Devices and Solid-State Circuits, pp. 479 – 48, 16-18 Dec (2003).

    1.  Ho, H.P. and Wong, C.L., Application of spectral surface plasmon resonance for gas pressure sensing. Electron Devices Meeting 2002 Proceedings, 2002 IEEE Hong Kong, pp.73 – 77, 22 June (2002).

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